Placenta neoplasm

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Placenta Neoplasm

A placenta neoplasm is a rare type of tumor that occurs in the placenta, an organ that develops in the uterus during pregnancy and provides oxygen and nutrients to the growing fetus while removing waste products from the baby's blood. Placenta neoplasms can be benign (non-cancerous) or malignant (cancerous), with the latter being extremely rare. These tumors can have significant implications for both maternal and fetal health, depending on their nature, size, and location.

Types of Placenta Neoplasms[edit | edit source]

Placenta neoplasms can be classified into several types, the most common of which include:

  • Choriocarcinoma: A fast-growing, malignant tumor that can develop in the uterus after a normal pregnancy, miscarriage, abortion, or molar pregnancy. It is a type of gestational trophoblastic disease (GTD).
  • Placental site trophoblastic tumor (PSTT): A rare form of GTD that arises from the site where the placenta attaches to the lining of the uterus.
  • Hydatidiform mole: Also known as a molar pregnancy, it is a benign condition in which the placenta develops into an abnormal mass of cysts rather than a normal placenta.

Symptoms and Diagnosis[edit | edit source]

Symptoms of placenta neoplasms vary depending on the type and severity of the tumor. Common symptoms may include vaginal bleeding, severe nausea and vomiting, and rapid enlargement of the uterus. Diagnosis typically involves a combination of ultrasound imaging, blood tests to measure levels of human chorionic gonadotropin (hCG), and, in some cases, magnetic resonance imaging (MRI) or computed tomography (CT) scans.

Treatment[edit | edit source]

Treatment for placenta neoplasms depends on the type, size, and location of the tumor, as well as whether it is benign or malignant. Options may include:

  • Surgery: Removal of the tumor or, in some cases, the entire uterus (hysterectomy).
  • Chemotherapy: Used primarily for malignant tumors, such as choriocarcinoma, to kill cancer cells.
  • Monitoring: In cases of benign conditions like a hydatidiform mole, careful monitoring of hCG levels after the mole has been removed to ensure that no malignant cells remain.

Prognosis[edit | edit source]

The prognosis for placenta neoplasms varies widely. Benign conditions like hydatidiform moles have an excellent prognosis with proper treatment and monitoring. Malignant tumors, such as choriocarcinoma, also have a good prognosis if detected early and treated aggressively. However, untreated or late-detected cases can lead to serious complications, including metastasis and death.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD