Polymer fume fever

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Polymer fume fever
Polytetrafluoroethylene.svg
Synonyms Teflon flu
Pronounce N/A
Specialty N/A
Symptoms Fever, chills, cough, sore throat, chest tightness, dyspnea
Complications Pneumonia, pulmonary edema
Onset Within a few hours of exposure
Duration 12 to 48 hours
Types N/A
Causes Inhalation of polytetrafluoroethylene (PTFE) fumes
Risks Occupational exposure in industrial settings
Diagnosis Based on clinical history and symptoms
Differential diagnosis Influenza, common cold, bronchitis
Prevention Avoiding exposure to PTFE fumes, using ventilation and respiratory protection
Treatment Supportive care, oxygen therapy, antipyretics
Medication N/A
Prognosis Generally good with full recovery
Frequency Rare
Deaths N/A


An illness caused by inhalation of fumes from heated polytetrafluoroethylene


Polymer fume fever is an acute illness caused by the inhalation of fumes released when polytetrafluoroethylene (PTFE) is heated to high temperatures. This condition is characterized by flu-like symptoms and is often associated with occupational exposure in industries where PTFE is used.

Causes[edit | edit source]

Polymer fume fever occurs when PTFE, a type of fluoropolymer, is heated above 300°C (572°F), releasing toxic fumes. These fumes contain ultrafine particles and gaseous products such as hydrogen fluoride and carbonyl fluoride. Workers in industries such as plastics manufacturing, metal coating, and cooking with non-stick cookware are at risk of exposure.

Symptoms[edit | edit source]

The symptoms of polymer fume fever typically appear several hours after exposure and include:

These symptoms usually resolve within 24 to 48 hours without long-term effects, but repeated exposure can lead to more severe respiratory issues.

Diagnosis[edit | edit source]

Diagnosis of polymer fume fever is primarily based on the patient's history of exposure to PTFE fumes and the presence of characteristic symptoms. There are no specific laboratory tests for this condition, but chest X-ray and pulmonary function tests may be conducted to rule out other respiratory conditions.

Prevention[edit | edit source]

Preventing polymer fume fever involves controlling exposure to PTFE fumes. This can be achieved by:

Treatment[edit | edit source]

Treatment for polymer fume fever is mainly supportive. Patients are advised to rest and stay hydrated. Nonsteroidal anti-inflammatory drugs (NSAIDs) may be used to alleviate symptoms such as fever and muscle pain. In severe cases, oxygen therapy may be required.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD