Postmyocardial infarction syndrome

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Postmyocardial Infarction Syndrome (also known as Dressler's Syndrome) is a secondary form of pericarditis that occurs in the setting of injury to the heart or the pericardium (the outer lining of the heart). It is a complication that can occur after a myocardial infarction (heart attack).

Etiology[edit | edit source]

The exact cause of Postmyocardial Infarction Syndrome is not known, but it is believed to be an immune response to heart damage. The body's immune system may mistake the heart tissue as foreign and attack it, leading to inflammation.

Symptoms[edit | edit source]

Symptoms of Postmyocardial Infarction Syndrome typically occur weeks to months after a heart attack. They may include chest pain, fever, and fatigue. The chest pain is usually worse when lying down and improves when sitting up or leaning forward.

Diagnosis[edit | edit source]

Diagnosis of Postmyocardial Infarction Syndrome is typically made based on the patient's symptoms and history of a recent heart attack. Additional tests such as an electrocardiogram (ECG), echocardiogram, and blood tests may be used to confirm the diagnosis.

Treatment[edit | edit source]

Treatment for Postmyocardial Infarction Syndrome typically involves medications to reduce inflammation and control pain. These may include nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and colchicine. In severe cases, surgery may be required to remove the inflamed pericardium.

Prognosis[edit | edit source]

With treatment, most people with Postmyocardial Infarction Syndrome recover fully. However, the condition can recur in some cases.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD