Predictive marker
Predictive Marker
A predictive marker is a biomarker that is used to identify the likelihood of a patient's response to a particular treatment. These markers are often used in oncology to predict the effectiveness of certain chemotherapy drugs or radiation therapy.
Overview[edit | edit source]
Predictive markers are used to help determine the most effective treatment for a patient. They are often used in conjunction with other diagnostic tests and medical history to make a comprehensive treatment plan. Predictive markers can be found in the blood, tissue, or other bodily fluids and can be identified through various laboratory tests.
Types of Predictive Markers[edit | edit source]
There are several types of predictive markers used in medicine today. Some of the most common include:
- Genetic markers: These are changes in DNA that can predict a person's risk of developing certain diseases or their response to treatment.
- Protein markers: These are changes in the levels of certain proteins in the body that can indicate a disease or condition.
- Metabolic markers: These are changes in the body's metabolic processes that can indicate a disease or condition.
Use in Oncology[edit | edit source]
In oncology, predictive markers are often used to determine the most effective treatment for a patient. For example, the presence of the HER2 gene in breast cancer patients can predict a positive response to Herceptin, a targeted therapy drug. Similarly, the presence of the KRAS gene in colorectal cancer patients can predict a negative response to EGFR inhibitor drugs.
Future Directions[edit | edit source]
The field of predictive markers is constantly evolving, with new markers being discovered and validated regularly. The use of predictive markers in personalized medicine is a promising area of research, with the potential to greatly improve patient outcomes.
See Also[edit | edit source]
- Biomarker
- Diagnostic test
- Oncology
- Chemotherapy
- Radiation therapy
- Genetic marker
- Protein marker
- Metabolic marker
- HER2
- KRAS
- EGFR
- Herceptin
- Personalized medicine
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Contributors: Prab R. Tumpati, MD
