Primary peritoneal cancer

Primary peritoneal cancer (PPC) is a rare cancer that develops in the peritoneum, a thin, delicate sheet that lines the inside wall of the abdomen and covers the uterus and extends over the bladder and rectum. PPC is a close relative of ovarian cancer, which is why it is often mistaken for ovarian cancer. It is also known as extraovarian primary peritoneal carcinoma (EOPPC) and serous surface papillary carcinoma.

Causes[edit | edit source]

The exact cause of PPC is unknown. However, it is believed to be associated with the BRCA1 and BRCA2 gene mutations. Women with these mutations have a higher risk of developing both breast and ovarian cancer. PPC is more common in women who have had their ovaries removed to prevent ovarian cancer.

Symptoms[edit | edit source]

The symptoms of PPC are similar to those of ovarian cancer. They include:

Abdominal bloating or swelling
Quick feeling of fullness while eating
Weight loss
Discomfort in the pelvis area
Changes in bowel habits, such as constipation
A frequent need to urinate

Diagnosis[edit | edit source]

Diagnosis of PPC is often difficult because the symptoms are non-specific and similar to other conditions. It is often diagnosed at an advanced stage. The following tests may be used to diagnose PPC:

Physical exam and history
Pelvic exam
Ultrasound
CA 125 assay
CT scan
Biopsy

Treatment[edit | edit source]

Treatment of PPC is similar to the treatment for advanced ovarian cancer. It may include surgery to remove as much of the cancer as possible, followed by chemotherapy. In some cases, radiation therapy may be used.

Prognosis[edit | edit source]

The prognosis for PPC is generally poor, as the disease is often advanced when diagnosed. However, survival rates can vary greatly depending on the stage of the cancer and the patient's overall health.

See also[edit | edit source]

Primary peritoneal cancer Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.