Propargyl alcohol

From WikiMD's Food, Medicine & Wellness Encyclopedia

Propargyl alcohol, also known by its systematic name, 2-Propyn-1-ol, is an organic compound with the formula C3H4O. It is a colorless liquid with a sharp, pungent odor, classified as an alkyne alcohol. Propargyl alcohol is used in the synthesis of various chemical compounds, serving as a building block in organic synthesis, and has applications in the pharmaceutical and agricultural industries.

Properties[edit | edit source]

Propargyl alcohol has a molecular weight of 56.06 g/mol and boils at 114 °C. It is soluble in water and most organic solvents. Being an alkyne, it features a triple bond between the first and second carbon atoms, which is a key functional group that reacts with a range of reagents to form new bonds.

Production[edit | edit source]

The production of propargyl alcohol typically involves the reaction of formaldehyde with acetylene in the presence of a base, such as potassium hydroxide. This process yields propargyl alcohol along with water as a byproduct.

Applications[edit | edit source]

Propargyl alcohol is utilized in various chemical syntheses. It acts as a precursor to propargyl ethers, which are important intermediates in the production of pharmaceuticals and agrochemicals. Additionally, it is used in the manufacture of corrosion inhibitors, which are chemicals that prevent corrosion in metal pipelines and storage tanks. Propargyl alcohol is also employed in the synthesis of flame retardants and polymers.

Safety[edit | edit source]

Handling propargyl alcohol requires caution due to its flammability and potential health hazards. It can cause irritation to the skin, eyes, and respiratory system upon exposure. Proper protective equipment, such as gloves and goggles, should be worn when working with this chemical. In case of skin or eye contact, the affected area should be rinsed immediately with plenty of water.

Environmental Impact[edit | edit source]

The environmental impact of propargyl alcohol is subject to its usage and disposal practices. Being a volatile organic compound (VOC), it can contribute to air pollution if not properly managed. It is important to follow all regulatory guidelines for the storage, use, and disposal of propargyl alcohol to minimize its environmental footprint.

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Contributors: Prab R. Tumpati, MD