Proximal tubule
Proximal Tubule
The proximal tubule is a part of the nephron, the functional unit of the kidney. It is the first part of the renal tubule system and plays a crucial role in the reabsorption and secretion of various substances.
Structure[edit | edit source]
The proximal tubule is divided into two segments: the proximal convoluted tubule (PCT) and the proximal straight tubule (PST). The PCT is located in the renal cortex, while the PST extends into the renal medulla.
Function[edit | edit source]
The primary function of the proximal tubule is to reabsorb around 65% of the glomerular filtrate. This includes sodium, glucose, amino acids, and water. It also secretes substances such as hydrogen ions, ammonia, and urea.
Clinical Significance[edit | edit source]
Diseases of the proximal tubule can lead to various clinical conditions. For example, Fanconi syndrome is a disorder of the proximal tubule that results in the loss of essential substances in the urine. Renal tubular acidosis is another condition that can occur due to dysfunction of the proximal tubule.
See Also[edit | edit source]
References[edit | edit source]
| Proximal tubule Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
