Prurigo pigmentosa

Prurigo Pigmentosa is a rare, chronic inflammatory skin disease. It is characterized by recurrent itchy red bumps that later develop into a reticulated hyperpigmentation after the inflammation subsides. The disease was first described in Japan by Nagashima et al. in 1971, and it is more prevalent in the Japanese population. However, cases have been reported worldwide. The exact cause of Prurigo Pigmentosa is unknown, but it is thought to be associated with ketosis, diet changes, and friction on the skin.

Symptoms

The primary symptom of Prurigo Pigmentosa is the sudden onset of itchy red bumps on the skin. These bumps typically form a net-like pattern, and they are most commonly found on the back, chest, and neck. After the inflammation subsides, the bumps leave behind a dark, reticulated pigmentation.

Causes

The exact cause of Prurigo Pigmentosa is unknown. However, several factors have been associated with the disease. These include ketosis, diet changes, and friction on the skin. Some studies have also suggested a possible link between Prurigo Pigmentosa and diabetes mellitus, anorexia nervosa, and Helicobacter pylori infection.

Diagnosis

Diagnosis of Prurigo Pigmentosa is primarily based on the characteristic clinical presentation and histopathological findings. The disease is often misdiagnosed due to its rarity and the lack of awareness among physicians. A skin biopsy is usually required to confirm the diagnosis.

Treatment

Treatment of Prurigo Pigmentosa primarily involves the use of antibiotics such as doxycycline and minocycline. Topical steroids and oral antihistamines may also be used to manage the symptoms. In some cases, dietary modifications may be recommended.

Prognosis

The prognosis for Prurigo Pigmentosa is generally good. The disease is chronic and recurrent, but it does not affect the overall health or lifespan of the patient. However, the recurrent nature of the disease can cause significant distress and impact the quality of life.

See Also

• Dermatology
• Skin disease
• Inflammatory skin diseases

References

Prurigo pigmentosa Resources
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