Psoriatic juvenile idiopathic arthritis
Other Names: Juvenile psoriatic arthritis; Psoriasis-related JIA; Psoriasis-related juvenile idiopathic arthritis
Psoriatic juvenile idiopathic arthritis is a subtype of juvenile idiopathic arthritis that is characterized by both arthritis and psoriasis.
Cause and risk factors[edit | edit source]
Although the underlying cause of psoriatic juvenile idiopathic arthritis is currently unknown (idiopathic), it is thought to occur due to a combination of genetic and environmental factors. It is very rare for more than one member of a family to have juvenile arthritis; however, research suggests that having a family member with juvenile arthritis or any autoimmune disease may increase the risk of having juvenile arthritis, in general.
Signs and symptoms [edit | edit source]
signs and symptoms may include dactylitis (inflammation and swelling of an entire finger or toe); nail pitting or splitting; and eye problems. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. 80%-99% of people have these symptoms
- Abnormality of tumor necrosis factor secretion
30%-79% of people have these symptoms
- Antinuclear antibody positivity
- Arthralgia(Joint pain)
- Enthesitis
- Finger dactylitis(Sausage fingers)
- Nail pits(Nail pitting)
- Oligoarthritis
- Polyarticular arthritis
- Pruritus(Itching)
- Psoriasiform dermatitis
- Toe dactylitis(Sausage toes)
5%-29% of people have these symptoms
- Abnormality of the knee
- Abnormality of the shoulder
- Abnormality of the wrist(Abnormalities of the wrists)
- Generalized morning stiffness
- Malar rash
- Psoriasiform lesion
- Reduced visual acuity(Decreased clarity of vision)
Treatment[edit | edit source]
The medication(s) listed below have been approved by the Food and Drug Administration (FDA) as orphan products for treatment of this condition.
- Methotrexate oral solution (Brand name: Xatmep) methotrexate oral solution (Xatmep) was approved for the treatment of oligoarticular juvenile idiopathic arthritis (persistent oligoarthritis, psoriatic juvenile idiopathic arthritis, enthesitis-related arthritis, or undifferentiated arthritis) and polyarticular juvenile idiopathic arthritis in children 0 through 16 years of age.
NIH genetic and rare disease info[edit source]
Psoriatic juvenile idiopathic arthritis is a rare disease.
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