Quinpirole

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Quinpirole


Quinpirole is a psychoactive drug and research chemical which acts as a dopamine receptor agonist. It is selective for the D2 and D3 dopamine receptor subtypes.

Chemistry[edit | edit source]

Quinpirole is a synthetic compound of the quinoline class. It is structurally related to other quinoline-based dopamine receptor agonists such as quinpirole hydrochloride and quinpirole sulfate.

Pharmacology[edit | edit source]

Quinpirole exerts its effects by binding to and activating the D2 and D3 dopamine receptors. These receptors are part of the dopamine system, which plays a major role in reward, pleasure, motor function and many other important neurological processes. By activating these receptors, quinpirole can produce a wide range of effects, including motor control improvements, antipsychotic effects, and potentially addictive behaviors.

Medical Use[edit | edit source]

While quinpirole itself is not currently used in medicine, it is a valuable tool in research due to its selective action on the D2 and D3 dopamine receptors. It is often used in animal studies to investigate the role of these receptors in behavior and disease.

Side Effects[edit | edit source]

As with any drug that modifies brain chemistry, quinpirole can have side effects. These can include nausea, vomiting, insomnia, and hallucinations. In animal studies, it has also been associated with the development of compulsive behaviors.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD