Rabbit syndrome
Rabbit syndrome is a rare[1] form of extrapyramidal side effect of antipsychotic drugs in which perioral tremors occur at a rate of approximately 5 Hz. Rabbit syndrome is characterized by involuntary, fine, rhythmic motions of the mouth along a vertical plane, without involvement of the tongue,[2][3] and resembling the chewing movements of a rabbit.[4] It is usually seen after years of pharmacotherapy, and is more prominent with high potency drugs like haloperidol, fluphenazine, and pimozide. There is also a low incidence with thioridazine, clozapine, olanzapine, aripiprazole,[5] and low doses of risperidone.
Rabbit syndrome can be treated with anticholinergic drugs. It generally disappears within a few days of treatment but may re-emerge after anticholinergic treatment is stopped. Another treatment strategy is to switch the patient to an atypical antipsychotic with high anti-cholinergic properties.[3]
References[edit | edit source]
- ↑ , Prevalence of the rabbit syndrome, American Journal of Psychiatry, 1986, Vol. 143(Issue: 5), pp. 656–7, DOI: 10.1176/ajp.143.5.656, PMID: 2870650,
- ↑ , The rabbit syndrome. A peculiar extrapyramidal reaction, Canadian Psychiatric Association Journal, 1972, Vol. 17(Issue: 2), pp. Suppl 2:SS69–, DOI: 10.1177/07067437720176S213, PMID: 5042912,
- ↑ 3.0 3.1 , Newer antipsychotics and the rabbit syndrome, Clinical Practice and Epidemiology in Mental Health, 2007, Vol. 3, pp. 6, DOI: 10.1186/1745-0179-3-6, PMID: 17562001, PMC: 1914060,
- ↑ , Antipsychotic-induced rabbit syndrome: Epidemiology, management and pathophysiology, CNS Drugs, 2004, Vol. 18(Issue: 4), pp. 213–20, DOI: 10.2165/00023210-200418040-00002, PMID: 15015902,
- ↑ , Aripiprazole-induced rabbit syndrome in a drug-naive schizophrenic patient, Schizophrenia Research, 2008, Vol. 103(Issue: 1–3), pp. 341–2, DOI: 10.1016/j.schres.2008.01.008, PMID: 18262773,
| Rabbit syndrome Resources | |
|---|---|
 |
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
