Rickettsia australis
Rickettsia australis is a species of bacteria in the genus Rickettsia. It is the causative agent of a condition known as Queensland tick typhus, a disease primarily found in Australia and transmitted through the bite of infected ticks.
Taxonomy[edit | edit source]
Rickettsia australis belongs to the genus Rickettsia, which is a part of the phylum Proteobacteria, class Alphaproteobacteria, and order Rickettsiales. The genus Rickettsia is further divided into four groups: spotted fever, typhus, ancestral, and transitional. Rickettsia australis is a member of the spotted fever group.
Morphology[edit | edit source]
Like other members of the genus Rickettsia, Rickettsia australis is a small, rod-shaped bacterium. It is Gram-negative, meaning it does not retain the crystal violet stain used in the Gram stain procedure, but is instead colored red or pink.
Pathogenesis[edit | edit source]
Rickettsia australis is the causative agent of Queensland tick typhus, a condition characterized by fever, headache, and a rash. The bacterium is transmitted to humans through the bite of an infected tick, specifically the species Ixodes holocyclus and Amblyomma triguttatum. Once in the human body, the bacteria invade the endothelial cells lining the blood vessels, leading to vasculitis.
Diagnosis and Treatment[edit | edit source]
Diagnosis of Queensland tick typhus is typically based on clinical symptoms and a history of tick exposure. Laboratory testing can confirm the diagnosis, with serology being the most commonly used method. Treatment typically involves the use of antibiotics, with doxycycline being the drug of choice.
Epidemiology[edit | edit source]
Queensland tick typhus is primarily found in the eastern coastal regions of Australia, particularly in the states of Queensland and New South Wales. The disease is most common during the warmer months when ticks are most active.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD