SB-258585

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SB-258585 is a drug that acts as a potent and selective antagonist for the 5-HT6 receptor. It has been used in scientific research to explore the role of 5-HT6 in the brain, and has been found to produce cognitive enhancing effects in animal studies.

Pharmacology[edit | edit source]

SB-258585 is a 5-HT6 receptor antagonist. The 5-HT6 receptor is a subtype of the 5-HT receptor that binds the endogenous neurotransmitter serotonin. It is thought to be involved in the regulation of cognition, mood, and anxiety, among other functions.

In animal studies, SB-258585 has been found to enhance cognitive performance. This effect is thought to be mediated by its action on the 5-HT6 receptor, although the exact mechanisms are not fully understood.

Research[edit | edit source]

Research into the effects of SB-258585 has primarily focused on its potential as a treatment for cognitive disorders such as Alzheimer's disease and schizophrenia. In animal models of these conditions, SB-258585 has been found to improve cognitive performance.

In addition to its potential therapeutic applications, SB-258585 has also been used as a tool in scientific research to better understand the role of the 5-HT6 receptor in the brain.

See also[edit | edit source]

References[edit | edit source]


SB-258585 Resources

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Contributors: Prab R. Tumpati, MD