SC-236

From WikiMD's Wellness Encyclopedia



SC-236 is a selective cyclooxygenase-2 (COX-2) inhibitor that has been studied for its potential use in treating inflammation and pain. COX-2 inhibitors are a class of drugs that specifically target the COX-2 enzyme, which is responsible for the synthesis of pro-inflammatory prostaglandins.

Mechanism of Action[edit | edit source]

SC-236 works by selectively inhibiting the COX-2 enzyme, thereby reducing the production of pro-inflammatory prostaglandins. This action helps to alleviate inflammation and pain without affecting the COX-1 enzyme, which is important for maintaining the protective lining of the stomach and regulating blood platelets.

Pharmacokinetics[edit | edit source]

The pharmacokinetics of SC-236 involve its absorption, distribution, metabolism, and excretion. SC-236 is absorbed into the bloodstream after oral administration and is distributed throughout the body. It is metabolized primarily in the liver and excreted through the kidneys.

Clinical Applications[edit | edit source]

SC-236 has been investigated for its potential use in treating conditions such as arthritis, cancer, and other inflammatory diseases. Its selective inhibition of COX-2 makes it a promising candidate for reducing inflammation with fewer gastrointestinal side effects compared to non-selective NSAIDs.

Research and Development[edit | edit source]

Research on SC-236 has focused on its efficacy and safety profile. Studies have shown that SC-236 can effectively reduce inflammation and pain in animal models. However, further clinical trials are necessary to fully understand its potential benefits and risks in humans.

Side Effects[edit | edit source]

As with other COX-2 inhibitors, potential side effects of SC-236 may include cardiovascular risks, such as an increased risk of heart attack or stroke. Gastrointestinal side effects are generally less common compared to non-selective NSAIDs.

Regulatory Status[edit | edit source]

As of the latest updates, SC-236 is still under investigation and has not been approved for clinical use by major regulatory agencies such as the FDA or EMA.

Also see[edit | edit source]

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Contributors: Prab R. Tumpati, MD