Drospirenone/ethinylestradiol/levomefolic acid

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Drospirenone/Ethinylestradiol/Levomefolic Acid[edit | edit source]

Drospirenone/Ethinylestradiol/Levomefolic Acid is a combination medication used for hormonal contraception. It contains three active ingredients: drospirenone, ethinylestradiol, and levomefolic acid. This article will provide a detailed overview of these components and their functions, as well as the uses, dosage, side effects, and precautions associated with this medication.

Components[edit | edit source]

Drospirenone[edit | edit source]

Drospirenone is a synthetic progestin, which is a type of hormone that mimics the effects of progesterone in the body. It works by preventing ovulation, thickening the cervical mucus to inhibit sperm penetration, and altering the lining of the uterus to prevent implantation of a fertilized egg. Drospirenone also has anti-androgenic properties, meaning it can reduce the effects of male hormones in the body.

Ethinylestradiol[edit | edit source]

Ethinylestradiol is a synthetic estrogen, which is a hormone that regulates the menstrual cycle and promotes the development of female sexual characteristics. It works by inhibiting the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), thereby preventing the release of an egg from the ovary. Ethinylestradiol also helps to stabilize the endometrium (the lining of the uterus) to prevent breakthrough bleeding.

Levomefolic Acid[edit | edit source]

Levomefolic acid, also known as L-methylfolate, is the active form of folic acid. Folic acid is a B-vitamin that plays a crucial role in DNA synthesis and cell division. Levomefolic acid helps to support the overall health of the reproductive system and may reduce the risk of certain birth defects when taken during pregnancy.

Uses[edit | edit source]

Drospirenone/Ethinylestradiol/Levomefolic Acid is primarily used as a combined oral contraceptive, commonly known as the birth control pill. It is taken daily to prevent pregnancy by inhibiting ovulation, thickening cervical mucus, and altering the uterine lining. This medication may also be prescribed to regulate menstrual cycles, reduce menstrual pain, and treat symptoms of premenstrual dysphoric disorder (PMDD).

Dosage[edit | edit source]

The dosage of Drospirenone/Ethinylestradiol/Levomefolic Acid may vary depending on the specific brand and formulation prescribed. It is typically taken orally once daily, preferably at the same time each day, for 21 consecutive days followed by a 7-day hormone-free interval. During the hormone-free interval, withdrawal bleeding similar to a menstrual period may occur.

It is important to follow the instructions provided by your healthcare provider and read the patient information leaflet that comes with the medication. If you have any questions or concerns about the dosage, consult your healthcare provider or pharmacist.

Side Effects[edit | edit source]

Common side effects of Drospirenone/Ethinylestradiol/Levomefolic Acid may include nausea, breast tenderness, headache, mood changes, and breakthrough bleeding. These side effects are usually mild and tend to improve with continued use. However, if any of these side effects persist or worsen, it is important to seek medical attention.

Serious side effects of this medication are rare but may include blood clots, high blood pressure, liver problems, and allergic reactions. Contact your healthcare provider immediately if you experience symptoms such as severe abdominal pain, chest pain, shortness of breath, severe headache, or swelling of the hands or feet.

Precautions[edit | edit source]

Before taking Drospirenone/Ethinylestradiol/Levomefolic Acid, inform your healthcare provider about any existing medical conditions, allergies, or medications you are currently taking. This medication may not be suitable for individuals with a history of blood clots, heart disease, liver disease, certain cancers, or uncontrolled high blood pressure.

It is important to note that Drospirenone/Ethinylestradiol/Levomefolic Acid does not protect against sexually transmitted infections (STIs). Therefore, additional barrier methods of contraception, such as condoms, should be used to reduce the risk of STIs.

Conclusion[edit | edit source]

Drospirenone/Ethinylestradiol/Levomefolic Acid is a combination medication that provides effective hormonal contraception. It contains drospirenone, ethinylestradiol, and levomefolic acid, which work together to prevent pregnancy and regulate menstrual cycles. While generally well-tolerated, it is important to be aware of the potential side effects and precautions associated with this medication. If you have any concerns or questions, consult your healthcare provider for personalized advice.

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Contributors: Prab R. Tumpati, MD