Samarium-153
Samarium-153 is a radioisotope of the element samarium, symbolized as Sm-153. It is a synthetic isotope, produced in nuclear reactors through the neutron bombardment of natural samarium.
Production[edit | edit source]
The production of Samarium-153 involves the irradiation of natural samarium in a nuclear reactor. The samarium absorbs a neutron, transforming it into Samarium-153. This process is known as neutron capture.
Properties[edit | edit source]
Samarium-153 is a beta emitter, meaning it emits beta particles during radioactive decay. It also emits a significant amount of gamma radiation, which allows it to be used in medical imaging. Its half-life is approximately 46.3 hours, making it suitable for therapeutic applications.
Medical Applications[edit | edit source]
Samarium-153 is used in medicine, particularly in the treatment of cancer. It is used in a form known as Samarium-153 lexidronam (Quadramet), which is a complex of Samarium-153 with a bone-seeking carrier molecule. This allows the radioisotope to be delivered directly to bone metastases, where it delivers a high dose of radiation to the cancer cells.
Samarium-153 lexidronam is used primarily in the treatment of bone metastases from prostate cancer, but it can also be used in the treatment of bone metastases from other types of cancer. It can also be used in the treatment of pain associated with bone metastases.
Safety[edit | edit source]
As with all radioisotopes, Samarium-153 must be handled with care to prevent unnecessary exposure to radiation. It is typically handled and administered by trained radiation therapy professionals.
See Also[edit | edit source]
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