Serrated polyposis syndrome

Serrated Polyposis Syndrome (SPS) is a medical condition characterized by the presence of multiple serrated polyps in the colon and rectum. It is a rare condition, but it is associated with an increased risk of developing colorectal cancer.

Definition

Serrated Polyposis Syndrome is defined by the World Health Organization (WHO) as either: having at least five serrated polyps proximal to the sigmoid colon with two or more of these being larger than 10mm; or having any number of serrated polyps occurring proximal to the sigmoid colon in an individual who has a first-degree relative with serrated polyposis; or having more than 20 serrated polyps of any size distributed throughout the colon.

Symptoms

Most people with Serrated Polyposis Syndrome do not have any symptoms. However, some people may experience abdominal pain, diarrhea, constipation, or rectal bleeding.

Diagnosis

The diagnosis of Serrated Polyposis Syndrome is made by colonoscopy, which allows the doctor to see the polyps in the colon and rectum. The polyps are then removed and examined under a microscope to confirm the diagnosis.

Treatment

The treatment for Serrated Polyposis Syndrome involves regular colonoscopies to monitor for the development of new polyps and to remove any that are found. In some cases, surgery may be required to remove larger polyps or sections of the colon.

Prognosis

With regular monitoring and treatment, the prognosis for people with Serrated Polyposis Syndrome is generally good. However, there is an increased risk of developing colorectal cancer, so regular check-ups are important.

See Also

• Colorectal cancer
• Colonoscopy
• Polyp
• Sigmoid colon

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