Siewert classification

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Siewert classification is a system used in the medical field to categorize adenocarcinoma of the esophagogastric junction (AEG). This classification system was developed by R. Siewert and H. Stein, and it is widely used in clinical practice and research.

Overview[edit | edit source]

The Siewert classification divides AEG into three types based on the location of the tumor epicenter.

  • Type I: The tumor's epicenter is located 1–5 cm above the anatomical cardia. These tumors are also known as distal esophageal adenocarcinomas.
  • Type II: The tumor's epicenter is located 1 cm above to 2 cm below the anatomical cardia. These tumors are also known as true cardia adenocarcinomas.
  • Type III: The tumor's epicenter is located 2–5 cm below the anatomical cardia. These tumors are also known as subcardial gastric adenocarcinomas.

Clinical Significance[edit | edit source]

The Siewert classification is significant in determining the surgical approach for AEG. Type I and II tumors are typically treated with esophagectomy, while Type III tumors are treated with gastrectomy. The classification also has prognostic implications, with different survival rates observed for the three types.

See Also[edit | edit source]

References[edit | edit source]


Siewert classification Resources
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Contributors: Prab R. Tumpati, MD