Silicone granuloma

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Silicone granuloma
Ultrasound image of silicone granuloma
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Nodule, inflammation, pain, swelling
Complications Infection, scarring
Onset Variable, often months to years after exposure
Duration Chronic
Types N/A
Causes Silicone injection or leakage
Risks Cosmetic surgery, breast implants, silicone injections
Diagnosis Ultrasound, biopsy
Differential diagnosis Lipoma, cyst, lymphoma
Prevention N/A
Treatment Surgical excision, corticosteroids, antibiotics
Medication N/A
Prognosis Variable, depends on extent and treatment
Frequency Rare
Deaths N/A


Mammogram showing silicone granuloma (MLO view)
Error creating thumbnail:
Mammogram showing silicone granuloma (CC view)

Silicone granuloma is a type of granuloma, a specific form of chronic inflammation, that is caused by the injection of silicone. It is a rare but serious complication that can occur after procedures such as breast augmentation or other types of cosmetic surgery where silicone is used.

Causes[edit | edit source]

Silicone granulomas are caused by the body's immune response to silicone that has leaked or migrated from a silicone-containing device, such as a breast implant. The body forms a granuloma, or a mass of immune cells, around the silicone in an attempt to isolate it.

Symptoms[edit | edit source]

Symptoms of silicone granuloma can vary depending on the location and size of the granuloma. They may include pain, redness, swelling, and the formation of a lump or mass. In some cases, silicone granulomas can lead to serious complications such as skin necrosis or infection.

Diagnosis[edit | edit source]

Diagnosis of silicone granuloma is typically made based on the patient's medical history, physical examination, and imaging studies such as ultrasound or magnetic resonance imaging (MRI). In some cases, a biopsy may be needed to confirm the diagnosis.

Treatment[edit | edit source]

Treatment of silicone granuloma typically involves removing the source of the silicone, if possible. This may involve surgery to remove a silicone-containing device such as a breast implant. In some cases, medication may be used to reduce inflammation and manage symptoms.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD