Simple sequence length polymorphism

Simple Sequence Length Polymorphisms (SSLPs) are used as genetic markers with Polymerase Chain Reaction (PCR). An SSLP is a type of polymorphism: a difference in DNA sequence amongst individuals. SSLPs are repeated sequences over varying base lengths in intergenic regions of deoxyribonucleic acid (DNA). Variance in the length of SSLPs can be used to understand genetic variance between two individuals in a certain species.^[1]

Applications[edit]

An example of the usage of SSLPs (microsatellites) is seen in a study by Rosenberg et al., in which Rosenberg and his team used SSLPs to cluster different continental races. The study was critical to Nicholas Wade's New York Times Bestseller, Before the Dawn: Recovering the Lost History of Our Ancestors.^[2]

Rosenberg Study[edit]

Rosenberg studied 377 SSLPs in 1000 people in 52 different regions of the world. By using PCR and Cluster analysis, Rosenberg was able to group individuals that had the same SSLPs . These SSLPs were extremely useful to the experiment because they do not affect the phenotypes of the individuals, thus being unaffected by natural selection.^[3]

This WikiMD article can only be edited by registered and verified editors. You can log in or register.

↑ King & Motulsky (2002). Science 298, 2342-2343 Rosenberg et al. (2002). Science 298, 2381-2385
↑ Wade, Nicholas (2006). Before the Dawn: Recovering the Lost History of Our Ancestors. Penguin Press.
↑ Rosenberg et al. (2002). Science 298, 2381-2385

Navigation-> Medicine - Wellness - Encyclopedia - Health topics - Diseases - Drugs - Gray's Anatomy - W8MD diet - Ketogenic diet - Recipes

Sponsored Health Resource

W8MD Weight Loss, Sleep & MedSpa

Looking for physician-supervised weight loss, semaglutide, tirzepatide, or GLP-1 receptor agonist options? W8MD helps eligible patients in New York City, Brooklyn, New Jersey, Connecticut, Pennsylvania, Delaware, and greater Philadelphia with medical weight loss, sleep medicine, and long-term maintenance support.

GLP-1 specials: Affordable GLP-1 injections NYC and Philadelphia starting from $29.99/week and up for semaglutide with insurance accepted for qualifying visits, and $45/week and up for tirzepatide with insurance accepted for qualifying visits. Self-pay options start from $59.99/week and up for semaglutide and $69.99/week and up for tirzepatide.

Book a W8MD appointment · View GLP-1 specials

Paid promotional message. Eligibility, pricing, insurance coverage, medication availability, and results vary. Medical evaluation required.

Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Translate page: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, தமிழ், తెలుగు, Urdu, ಕನ್ನಡ, Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, বাংলা
European español, Deutsch, français, Greek, português do Brasil, polski, română, русский, Nederlands, norsk, svenska, suomi, Italian
Middle Eastern & African عربى, Turkish, Persian, Hebrew, Afrikaans, isiZulu, Kiswahili,
Other Bulgarian, Hungarian, Czech, Swedish, മലയാളം, मराठी, ਪੰਜਾਬੀ, ગુજરાતી, Portuguese, Ukrainian

[1] King & Motulsky (2002). Science 298, 2342-2343 Rosenberg et al. (2002). Science 298, 2381-2385

[2] Wade, Nicholas (2006). Before the Dawn: Recovering the Lost History of Our Ancestors. Penguin Press.

[3] Rosenberg et al. (2002). Science 298, 2381-2385

[1]

[2]

[3]