Single palmar crease

Single palmar crease or simian crease is a single line that runs across the palm of the hand. People most often have three creases in their palms. The single palmar crease or simian line is the merging of two palmar creases, known in humans as the "proximal palmar crease" and the "distal palmar crease", and is occasionally associated with genetic abnormalities such as Down Syndrome.

Characteristics

The single palmar crease appears in approximately 1 out of 30 people. Males are twice as likely as females to have this condition. Some people have a single palmar crease on one hand, while others may have it on both. This crease can occur in isolation or as part of a genetic condition.

Associations

A single palmar crease is often associated with some genetic disorders, including:

• Down Syndrome: About half of people with Down Syndrome have a single palmar crease.
• Aarskog syndrome: This is a rare genetic condition associated with facial, limb, and genital abnormalities.
• Fetal alcohol syndrome: This condition is caused by alcohol exposure in the womb, and can lead to a range of developmental disorders.

Diagnosis

A single palmar crease is often noticed at birth, when the doctor performs a physical examination. If the crease is present and the doctor suspects a genetic disorder, further tests may be carried out, such as a karyotype to look for Down Syndrome.

Treatment

There is no specific treatment for a single palmar crease. Treatment will depend on whether the crease is part of a genetic disorder. In such cases, treatment will focus on managing the symptoms of the disorder.

See also

• Dermatoglyphics
• Palmistry

References

Single palmar crease Resources
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