Metaxalone
(Redirected from Skelaxin)
Muscle relaxant medication
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Metaxalone is a muscle relaxant medication used to treat muscle pain and muscle spasms. It is marketed under the brand name Skelaxin. Metaxalone is typically prescribed as part of a comprehensive treatment plan that includes physical therapy and rest.
Medical uses[edit | edit source]
Metaxalone is indicated for the relief of discomfort associated with acute, painful musculoskeletal conditions. It is often used in conjunction with other treatments such as physical therapy and rest to enhance its effectiveness.
Mechanism of action[edit | edit source]
The exact mechanism of action of metaxalone is not fully understood. However, it is believed to work by depressing the central nervous system (CNS), leading to a reduction in muscle spasms and pain. Unlike some other muscle relaxants, metaxalone does not directly relax tense skeletal muscles.
Pharmacokinetics[edit | edit source]
Metaxalone is administered orally and is absorbed through the gastrointestinal tract. It is metabolized in the liver and has an elimination half-life of approximately 9 hours. The drug is excreted primarily through the kidneys.
Side effects[edit | edit source]
Common side effects of metaxalone include:
Serious side effects, although rare, may include:
Contraindications[edit | edit source]
Metaxalone should not be used in individuals with known hypersensitivity to the drug or any of its components. It is also contraindicated in patients with significant liver or kidney impairment.
Interactions[edit | edit source]
Metaxalone may interact with other CNS depressants, including:
These interactions can enhance the sedative effects of metaxalone and increase the risk of respiratory depression.
Dosage[edit | edit source]
The typical dosage of metaxalone for adults and children over 12 years of age is 800 mg taken three to four times a day. The dosage may be adjusted based on the patient's response and tolerance to the medication.
See also[edit | edit source]
References[edit | edit source]
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