Sodium-dependent phosphate transport protein 1
Sodium-dependent phosphate transport protein 1 (SLC17A1) is a protein that in humans is encoded by the SLC17A1 gene. This protein is a member of the solute carrier family and is primarily located in the kidney where it plays a crucial role in the reabsorption of phosphate.
Function[edit | edit source]
The SLC17A1 protein is a voltage-driven phosphate transporter that functions in renal phosphate reabsorption. It is responsible for the transport of phosphate from the renal tubule into the bloodstream, a process that is essential for maintaining normal phosphate levels in the body.
Clinical significance[edit | edit source]
Mutations in the SLC17A1 gene have been associated with hypophosphatemic rickets, a rare disorder characterized by low levels of phosphate in the blood. This can lead to weak and soft bones, a condition known as rickets in children and osteomalacia in adults.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
- SLC17A1 at the National Center for Biotechnology Information
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Contributors: Prab R. Tumpati, MD