Sodium cellulose phosphate

Sodium cellulose phosphate is a chemical compound used in the medical field, particularly in the treatment of hypercalcemia and hypercalciuria. It is a sodium salt of cellulose, which is chemically modified to contain phosphate groups.

Chemical Structure

Sodium cellulose phosphate is a complex molecule. The cellulose backbone is made up of repeating glucose units, which are linked together by β-1,4-glycosidic bonds. The phosphate groups are attached to the hydroxyl groups of the glucose units, replacing the hydrogen atoms. The sodium ions are associated with the phosphate groups, balancing their negative charge.

Medical Uses

Sodium cellulose phosphate is primarily used to treat conditions related to high levels of calcium in the body. It works by binding to dietary calcium in the intestines, preventing its absorption into the bloodstream. This reduces the amount of calcium available in the body, helping to lower high calcium levels.

Hypercalcemia

Hypercalcemia is a condition characterized by abnormally high levels of calcium in the blood. It can be caused by various conditions, including hyperparathyroidism, cancer, and certain medications. Sodium cellulose phosphate is used as a treatment option for hypercalcemia, as it can help to reduce calcium levels in the blood.

Hypercalciuria

Hypercalciuria is a condition characterized by excessive amounts of calcium in the urine. It can lead to the formation of kidney stones and other complications. Sodium cellulose phosphate can be used to treat hypercalciuria by reducing the amount of calcium that is absorbed from the diet, thereby reducing the amount of calcium that is excreted in the urine.

Side Effects

Like all medications, sodium cellulose phosphate can cause side effects. These may include gastrointestinal symptoms such as bloating, gas, and diarrhea. In rare cases, it can cause a severe allergic reaction.

See Also

• Cellulose
• Hypercalcemia
• Hypercalciuria
• Phosphate