Somatostatin receptor 1

From WikiMD's WELLNESSPEDIA

Somatostatin receptor 1 (SSTR1) is a protein that in humans is encoded by the SSTR1 gene. It is one of the five somatostatin receptors.

Function[edit]

Somatostatin receptor 1 is a G protein-coupled receptor that is expressed in the pancreas, kidney, and central nervous system. It binds somatostatin, a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors.

Clinical significance[edit]

Alterations in somatostatin receptor 1 function have been associated with various diseases, including neuroendocrine tumors, Alzheimer's disease, and schizophrenia. In neuroendocrine tumors, somatostatin analogs can be used to target the somatostatin receptor 1 for diagnostic and therapeutic purposes.

See also[edit]

References[edit]


External links[edit]

  • SSTR1 at HGNC
  • SSTR1 at UniProt









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