Sorbitan monooleate

From WikiMD.com Medical Encyclopedia


Sorbitan Monooleate[edit | edit source]

Chemical structure of Sorbitan Monooleate

Sorbitan monooleate, also known as Span 80, is a nonionic surfactant and emulsifier derived from the dehydration of sorbitol and the esterification of the resulting sorbitan with oleic acid. It is commonly used in the formulation of cosmetics, pharmaceuticals, and food products due to its ability to stabilize emulsions.

Chemical Properties[edit | edit source]

Sorbitan monooleate is a viscous, amber-colored liquid at room temperature. It is characterized by its hydrophilic-lipophilic balance (HLB) value, which is approximately 4.3, indicating its suitability for use in water-in-oil (W/O) emulsions. The chemical formula of sorbitan monooleate is C24H44O6.

Applications[edit | edit source]

Sorbitan monooleate is widely used in various industries due to its emulsifying properties:

  • Cosmetics: It is used in the formulation of creams, lotions, and sunscreens to stabilize emulsions and improve texture.
  • Pharmaceuticals: It acts as an emulsifier in topical and oral drug formulations, enhancing the stability and bioavailability of active ingredients.
  • Food Industry: It is used as an emulsifier in baked goods, margarine, and chocolate products to improve texture and shelf life.

Safety and Regulations[edit | edit source]

Sorbitan monooleate is generally recognized as safe (GRAS) by the Food and Drug Administration (FDA) for use in food products. However, it is important to adhere to regulatory guidelines regarding its concentration in various applications to ensure consumer safety.

Related Pages[edit | edit source]

WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD