Split hand urinary anomalies spina bifida
Other Names: Czeizel-Losonci syndrome; Split-hand with obstructive uropathy, spina bifida, and diaphragmatic defects
Czeizel-Losonci syndrome (CLS) is an exceedingly rare, severe, congenital genetic malformation disorder characterized by split hand/split foot, hydronephrosis, and spina bifida. Spinal and skeletal manifestations were thoracolumbar scoliosis, spina bifida (spina bifida occulta or spina bifida cystic), Bochdalek diaphragmatic hernia, and radial defects. There have been no further descriptions in the literature since 1987.
NIH genetic and rare disease info[edit source]
Split hand urinary anomalies spina bifida is a rare disease.
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