SsRNA-RT virus

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SsRNA-RT virus is a type of virus that belongs to the category of retroviruses. These viruses are characterized by their single-stranded RNA (ssRNA) genomes and the use of reverse transcriptase (RT) enzyme to replicate their genetic material.

Characteristics[edit | edit source]

SsRNA-RT viruses are unique in their replication process. Unlike other viruses, they carry their genetic information in the form of ssRNA. Upon infection, the virus uses its RT enzyme to convert this ssRNA into double-stranded DNA (dsDNA). This dsDNA is then integrated into the host cell's genome, allowing the virus to replicate and produce new viral particles.

Replication Cycle[edit | edit source]

The replication cycle of SsRNA-RT viruses involves several steps. First, the virus attaches to a host cell and injects its ssRNA genome and RT enzyme. The RT enzyme then converts the ssRNA into dsDNA. This dsDNA is integrated into the host cell's genome by the viral enzyme integrase. The host cell's machinery is then used to produce new viral proteins and RNA, which are assembled into new viral particles.

Examples[edit | edit source]

Examples of SsRNA-RT viruses include HIV (Human Immunodeficiency Virus) and HTLV (Human T-lymphotropic virus). These viruses are known to cause severe diseases in humans, such as AIDS (Acquired Immunodeficiency Syndrome) and adult T-cell leukemia/lymphoma, respectively.

Treatment and Prevention[edit | edit source]

Treatment for diseases caused by SsRNA-RT viruses typically involves antiretroviral therapy, which aims to inhibit the replication of the virus. Prevention strategies include safe sex practices, needle exchange programs, and vaccination where available.

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Contributors: Prab R. Tumpati, MD