Stanniocalcin

Stanniocalcin (STC) is a hormone that was first discovered in fish and is involved in the regulation of serum calcium levels. In humans, there are two forms of the hormone, STC1 and STC2, which are produced by different genes. Both forms of the hormone have similar functions, but they are expressed in different tissues and have different effects on the body.

Function

Stanniocalcin plays a crucial role in the regulation of calcium and phosphate homeostasis. It is involved in the transport of calcium and phosphate across the gut and kidney, and it also plays a role in the regulation of bone metabolism.

In addition to its role in calcium and phosphate homeostasis, stanniocalcin also has other functions. For example, it has been found to be involved in the regulation of cell growth and cell differentiation, and it has been implicated in the regulation of inflammation and oxidative stress.

Clinical significance

Alterations in the expression of stanniocalcin have been associated with a number of diseases, including cancer, cardiovascular disease, and kidney disease. In particular, overexpression of STC1 has been found in a number of different types of cancer, and it has been suggested that it may play a role in tumor growth and progression.

In addition to its potential role in disease, stanniocalcin may also have therapeutic potential. For example, it has been suggested that it may be useful in the treatment of osteoporosis, due to its role in bone metabolism.

See also

• Calcium metabolism
• Phosphate homeostasis
• Bone metabolism

References

Stanniocalcin Resources
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