Steapsin

Steapsin is an enzyme that is secreted by the pancreas into the small intestine. It plays a crucial role in the digestive system, specifically in the digestion of fats.

Function

Steapsin, also known as pancreatic lipase, is responsible for breaking down triglycerides, which are the main constituents of body fat in humans and other animals, into monoglycerides and fatty acids. This process is essential for the absorption of dietary fats in the small intestine.

Production and Secretion

Steapsin is produced in the acinar cells of the pancreas and secreted into the small intestine through the pancreatic duct. The secretion of steapsin, like other pancreatic enzymes, is stimulated by the hormones secretin and cholecystokinin, which are released by the cells lining the small intestine in response to the presence of food.

Clinical Significance

Deficiency or malfunction of steapsin can lead to malabsorption of fats, resulting in steatorrhea, a condition characterized by the excretion of excessive amounts of fat in the feces. This can be caused by diseases such as chronic pancreatitis, cystic fibrosis, or pancreatic cancer.

On the other hand, overproduction of steapsin can lead to the breakdown of excess fats, which can contribute to the development of pancreatitis, a painful inflammation of the pancreas.

See Also

• Digestive enzyme
• Lipase
• Pancreas
• Digestive system