Stenbolone acetate

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Overview[edit | edit source]

Chemical structure of Stenbolone Acetate

Stenbolone acetate is a synthetic anabolic-androgenic steroid (AAS) that is derived from dihydrotestosterone (DHT). It was developed in the 1960s and is known for its anabolic properties with relatively low androgenic effects. Stenbolone acetate is an esterified form of stenbolone, which allows for a more prolonged release of the active steroid into the bloodstream.

Chemical Structure[edit | edit source]

Stenbolone acetate is chemically known as 2-methyl-4,5_-dihydro-_1-testosterone 17_-acetate. The acetate ester attached to the 17-beta hydroxyl group of the steroid molecule increases its lipophilicity, allowing for a slower release when administered intramuscularly.

Pharmacology[edit | edit source]

Stenbolone acetate exhibits a high anabolic to androgenic ratio, making it a preferred choice for athletes seeking muscle growth with minimal androgenic side effects. It promotes protein synthesis and nitrogen retention in muscles, leading to increased muscle mass and strength. Unlike some other AAS, stenbolone acetate does not aromatize into estrogen, reducing the risk of estrogenic side effects such as gynecomastia.

Medical Uses[edit | edit source]

Stenbolone acetate was initially developed for medical purposes, including the treatment of anemia and muscle wasting conditions. Its ability to stimulate erythropoiesis (red blood cell production) made it useful in treating certain types of anemia. However, due to the development of more effective and safer alternatives, its medical use has become limited.

Side Effects[edit | edit source]

As with other anabolic steroids, the use of stenbolone acetate can lead to a range of side effects. These may include:

  • Hepatotoxicity: Although less hepatotoxic than some oral steroids, prolonged use can still affect liver function.
  • Cardiovascular effects: Potential for increased blood pressure and adverse effects on cholesterol levels.
  • Androgenic effects: While lower than many other steroids, potential for acne, hair loss, and virilization in women exists.

Legal Status[edit | edit source]

Stenbolone acetate, like many anabolic steroids, is classified as a controlled substance in many countries. Its use is restricted to medical applications, and non-medical use is often illegal.

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Contributors: Prab R. Tumpati, MD