Stilbenoids

From WikiMD's Food, Medicine & Wellness Encyclopedia

Stilbenoids are a type of phenolic compounds that are produced by plants in response to pathogen attack. They are a subclass of polyphenols and include many important compounds such as resveratrol and pterostilbene.

Structure and Classification[edit | edit source]

Stilbenoids are characterized by a 1,2-diphenylethylene core structure. This core can be substituted with various functional groups, leading to a wide variety of different stilbenoids. They can be classified into three main types: monomeric, oligomeric, and polymeric stilbenoids.

Monomeric Stilbenoids[edit | edit source]

Monomeric stilbenoids consist of a single stilbene unit. The most well-known example is resveratrol, which is found in grapes and wine. Other examples include pterostilbene and piceatannol.

Oligomeric Stilbenoids[edit | edit source]

Oligomeric stilbenoids are made up of two or more stilbene units linked together. Examples include ε-viniferin and miyabenol C.

Polymeric Stilbenoids[edit | edit source]

Polymeric stilbenoids are composed of many stilbene units linked together. They are less common than monomeric and oligomeric stilbenoids, but examples do exist, such as hopeaphenol.

Biological Activity[edit | edit source]

Stilbenoids have been found to have a wide range of biological activities. They are best known for their antioxidant properties, but they also have anti-inflammatory, antiviral, antifungal, and anticancer activities.

Biosynthesis[edit | edit source]

Stilbenoids are synthesized in plants via the phenylpropanoid pathway. The key enzyme in this process is stilbene synthase, which catalyzes the conversion of coumaroyl-CoA and malonyl-CoA to stilbenoids.

See Also[edit | edit source]

Stilbenoids Resources
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Contributors: Prab R. Tumpati, MD