Sue Wickner

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Wickner, sue

Sue Wickner is an American biochemist known for her significant contributions to the field of molecular biology. She is a senior investigator at the National Cancer Institute (NCI), which is part of the National Institutes of Health (NIH).

Early Life and Education

Sue Wickner was born in New York City. She earned her Bachelor of Science degree in Biology from Cornell University. She then pursued her Ph.D. in Biochemistry at the Albert Einstein College of Medicine.

Career

After completing her Ph.D., Wickner joined the National Cancer Institute as a postdoctoral fellow. She later became a senior investigator at the NCI, where she has conducted groundbreaking research in the areas of protein folding, molecular chaperones, and DNA replication.

Research Contributions

Wickner's research has focused on understanding the mechanisms of protein folding and the role of molecular chaperones in this process. Her work has provided insights into the function of chaperone proteins such as Hsp70 and ClpB, which are essential for maintaining cellular protein homeostasis.

One of her notable contributions is the study of the AAA+ ATPase family of proteins, which are involved in various cellular processes including DNA replication, transcription, and protein degradation. Wickner's research has elucidated the molecular mechanisms by which these proteins function, contributing to a deeper understanding of cellular biology.

Awards and Honors

Sue Wickner has received numerous awards for her contributions to science, including the NIH Director's Award and the American Society for Biochemistry and Molecular Biology (ASBMB) William C. Rose Award.

Personal Life

Wickner is married and has two children. She is an advocate for women in science and has mentored many young scientists throughout her career.

See Also

• Molecular chaperone
• Protein folding
• DNA replication
• National Cancer Institute
• National Institutes of Health