Syngeneic bone marrow transplantation

Syngeneic bone marrow transplantation is a type of bone marrow transplant that involves the transplantation of bone marrow from one identical twin to another. This type of transplant is unique because it does not involve the risk of graft-versus-host disease (GVHD), a common complication of other types of bone marrow transplants.

Procedure

The procedure for a syngeneic bone marrow transplant is similar to other types of bone marrow transplants. The donor's bone marrow is harvested, usually from the hip bone, in a surgical procedure. The marrow is then processed and given to the recipient through an intravenous (IV) line.

Benefits

The main benefit of a syngeneic bone marrow transplant is the lack of risk for GVHD. This is because the donor and recipient are genetically identical, so the recipient's immune system does not recognize the transplanted cells as foreign.

Risks

While syngeneic bone marrow transplants have less risk for GVHD, they do carry other risks. These include the risks associated with the surgical procedure to harvest the bone marrow, as well as potential complications from the transplant itself, such as infection.

Applications

Syngeneic bone marrow transplants are used to treat a variety of diseases, including certain types of cancer, anemia, and immune system disorders.

See also

• Bone marrow transplant
• Graft-versus-host disease
• Hematopoietic stem cell transplantation

Syngeneic bone marrow transplantation Resources
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