TCB-2

From WikiMD's Wellness Encyclopedia

TCB-2 is a psychedelic drug that was first synthesized by Alexander Shulgin. It is a potent and selective partial agonist for the serotonin 5-HT2A receptor, and is thought to be a research chemical that has been sold online as a designer drug.

Chemistry[edit | edit source]

TCB-2 is a member of the 25-NB family. It is structurally related to 2C-B and DOB, with the 4-bromo group of 2C-B replaced by a 4-chloro group, and the 2,5-dimethoxy groups of DOB replaced by 2,5-dichloro groups.

Pharmacology[edit | edit source]

TCB-2 is a partial agonist at the 5-HT2A receptor. It has a high affinity for this receptor, with a Ki of 0.25 nM. This makes it around 6 times more potent than DOB, and slightly less potent than LSD.

Effects[edit | edit source]

The effects of TCB-2 are not well documented, as it is a relatively new substance. However, it is thought to produce effects similar to other psychedelic drugs, such as visual hallucinations, altered perception, and euphoria.

Legal Status[edit | edit source]

In the United States, TCB-2 is not specifically listed as a controlled substance, but it may be considered an analog of 2C-B or DOB, which are Schedule I drugs under the Controlled Substances Act.

See Also[edit | edit source]

References[edit | edit source]


TCB-2 Resources
Wikipedia
WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD