TOM (psychedelic)

TOM (psychedelic) is a class of psychedelic drugs that were first synthesized in the late 20th century. The name "TOM" is an acronym for "2,5-dimethoxy-4-alkylthiophenethylamine." These substances are part of the larger family of phenethylamine compounds, which also includes other psychedelic drugs such as mescaline and 2C-B.

History

The TOM class of psychedelics was first synthesized by Alexander Shulgin, a renowned chemist and psychopharmacologist. Shulgin's work in the field of psychedelic research led to the discovery and synthesis of many new psychedelic compounds, including the TOMs. His findings were published in the book PiHKAL (Phenethylamines I Have Known And Loved), which has since become a seminal text in the field of psychedelic research.

Chemistry

TOM psychedelics are phenethylamine derivatives, meaning they are structurally related to naturally occurring compounds such as dopamine and adrenaline. The defining feature of the TOM class is the presence of a sulfur atom in the 4-position of the phenethylamine molecule, which is thought to contribute to their unique psychedelic effects.

Pharmacology

Like other psychedelic drugs, TOMs are thought to exert their effects primarily through interaction with the serotonin system in the brain. They are believed to act as agonists at the 5-HT2A receptor, which is known to play a key role in the regulation of mood, perception, and cognition.

Effects

The effects of TOM psychedelics can vary widely depending on the specific compound and the dose used. However, common effects reported by users include visual hallucinations, altered perception of time, enhanced introspection, and a sense of spiritual or mystical experience. As with all psychedelic drugs, the effects can be influenced by a variety of factors including the user's mindset, environment, and individual brain chemistry.

Legal Status

The legal status of TOM psychedelics varies by country and by specific compound. In many jurisdictions, they are classified as controlled substances, making their manufacture, sale, and possession illegal. However, there is ongoing debate and research into the potential therapeutic uses of these and other psychedelic substances.

See Also

• Psychedelic drug
• Phenethylamine
• Alexander Shulgin
• PiHKAL