Taniplon
Taniplon is a pharmaceutical drug that belongs to the class of anxiolytics. It is primarily used for the treatment of anxiety disorders and has a mechanism of action that involves modulation of the GABA (gamma-aminobutyric acid) system in the brain.
Mechanism of Action[edit | edit source]
Taniplon works by enhancing the effects of GABA, a neurotransmitter that inhibits neuronal activity in the central nervous system. This leads to a calming effect, which helps to alleviate symptoms of anxiety. The drug binds to specific sites on the GABA-A receptor, increasing the receptor's affinity for GABA and thereby potentiating its inhibitory effects.
Indications[edit | edit source]
Taniplon is indicated for the management of various anxiety disorders, including:
Dosage and Administration[edit | edit source]
The dosage of Taniplon varies depending on the severity of the condition and the patient's response to the medication. It is typically administered orally, and the dosage may be adjusted by a healthcare provider based on therapeutic response and tolerability.
Side Effects[edit | edit source]
Common side effects of Taniplon may include:
Serious side effects are rare but can include:
Contraindications[edit | edit source]
Taniplon is contraindicated in patients with:
- Severe hepatic impairment
- Hypersensitivity to the drug or any of its components
Interactions[edit | edit source]
Taniplon may interact with other medications, including:
- Alcohol
- Other CNS depressants
- Certain antidepressants
Pharmacokinetics[edit | edit source]
Taniplon is well-absorbed from the gastrointestinal tract and reaches peak plasma concentrations within 1-2 hours after oral administration. It is metabolized primarily in the liver and excreted in the urine.
See Also[edit | edit source]
References[edit | edit source]
External Links[edit | edit source]
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Contributors: Prab R. Tumpati, MD