Terminal stria

From WikiMD's Wellness Encyclopedia

Terminal stria is a structure in the brain that is part of the limbic system. It is a white matter tract that connects the hippocampus to the septal nuclei and the nucleus accumbens. The terminal stria is also known as the stria terminalis.

Structure[edit | edit source]

The terminal stria is a C-shaped band of fibers running along the lateral wall of the ventricle from the amygdala to the septal nuclei. It is part of the limbic system, which is involved in emotion, memory, and behavior. The terminal stria is divided into two parts: the ventral and the dorsal stria terminalis. The ventral stria terminalis connects the amygdala to the nucleus accumbens, while the dorsal stria terminalis connects the amygdala to the septal nuclei.

Function[edit | edit source]

The terminal stria plays a crucial role in the limbic system, which is involved in emotion, memory, and behavior. It is particularly involved in the regulation of fear and anxiety responses. The terminal stria also plays a role in the reward system of the brain, connecting the amygdala to the nucleus accumbens, a key area involved in reward and pleasure.

Clinical significance[edit | edit source]

Abnormalities in the terminal stria have been associated with a number of psychiatric disorders, including anxiety disorders, post-traumatic stress disorder, and addiction. Research is ongoing to better understand the role of the terminal stria in these conditions and to develop potential treatments.

See also[edit | edit source]

Terminal stria Resources
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Contributors: Prab R. Tumpati, MD