Testosterone propionate/testosterone ketolaurate
(Redirected from Testosid-Depot)
An article about the combination of testosterone propionate and testosterone ketolaurate
Engineered Monoclonal Antibodies[edit source]
Engineered monoclonal antibodies are a class of biological therapies that are designed to target specific antigens on the surface of cells. These antibodies are produced using recombinant DNA technologies and are used in the treatment of various diseases, including cancer, autoimmune disorders, and infectious diseases.
Structure and Function[edit source]
Monoclonal antibodies are composed of two identical heavy chains and two identical light chains, forming a Y-shaped molecule. The tips of the "Y" contain the antigen-binding sites, which are highly specific to the target antigen. This specificity allows monoclonal antibodies to bind to their target with high affinity, blocking or modulating the function of the antigen.
Types of Engineered Monoclonal Antibodies[edit source]
There are several types of engineered monoclonal antibodies, each designed for specific therapeutic purposes:
- Chimeric antibodies: These antibodies are composed of murine (mouse) variable regions and human constant regions. They are less immunogenic than fully murine antibodies.
- Humanized antibodies: These antibodies are mostly human, with only the antigen-binding sites derived from murine sources. This reduces the risk of immune reactions.
- Fully human antibodies: These are entirely human in origin, produced using transgenic mice or phage display technologies.
- Bispecific antibodies: These antibodies are engineered to bind two different antigens simultaneously, offering unique therapeutic mechanisms.
Applications in Medicine[edit source]
Engineered monoclonal antibodies have revolutionized the treatment of many diseases:
- Cancer therapy: Monoclonal antibodies can target specific tumor antigens, leading to direct tumor cell killing or recruitment of immune cells to attack the tumor.
- Autoimmune diseases: By targeting specific components of the immune system, monoclonal antibodies can reduce inflammation and tissue damage in diseases such as rheumatoid arthritis and multiple sclerosis.
- Infectious diseases: Monoclonal antibodies can neutralize pathogens or their toxins, providing passive immunity or enhancing the host's immune response.
Production[edit source]
The production of engineered monoclonal antibodies involves several steps:
1. Antigen identification: The target antigen is identified and characterized. 2. Hybridoma technology: B cells from immunized animals are fused with myeloma cells to create hybridomas that produce the desired antibody. 3. Recombinant DNA technology: Genes encoding the antibody are cloned and expressed in suitable host cells, such as Chinese hamster ovary cells. 4. Purification and formulation: The antibodies are purified and formulated for clinical use.
Challenges and Future Directions[edit source]
While engineered monoclonal antibodies have shown great promise, there are challenges such as high production costs, potential for immune reactions, and the development of resistance. Ongoing research aims to improve antibody design, reduce immunogenicity, and enhance therapeutic efficacy.
Related Pages[edit source]
Testosterone propionate/testosterone ketolaurate is a combination of two androgen and anabolic steroid (AAS) medications used in the treatment of hypogonadism in males and certain types of breast cancer in females. This combination is administered via intramuscular injection and is designed to provide both immediate and sustained release of testosterone.
Pharmacology[edit | edit source]
Testosterone propionate is a short-acting ester of testosterone, which allows for rapid onset of action. It is typically absorbed quickly into the bloodstream, providing an initial surge in testosterone levels. Testosterone ketolaurate, on the other hand, is a longer-acting ester, which is absorbed more slowly, providing a more sustained release of testosterone over time. This combination is intended to maintain stable testosterone levels with less frequent dosing compared to testosterone propionate alone.
Medical Uses[edit | edit source]
The primary medical use of testosterone propionate/testosterone ketolaurate is in the treatment of male hypogonadism, a condition characterized by low testosterone levels. Symptoms of hypogonadism can include reduced libido, fatigue, depression, and loss of muscle mass. By supplementing testosterone, these symptoms can be alleviated.
In females, this combination may be used in the treatment of certain types of breast cancer, particularly in postmenopausal women. The androgenic effects of testosterone can help counteract the growth of estrogen-dependent tumors.
Side Effects[edit | edit source]
Common side effects of testosterone therapy can include acne, oily skin, increased body hair, and mood changes. More serious side effects may include cardiovascular disease, liver dysfunction, and prostate cancer in males. It is important for patients to be monitored regularly by a healthcare provider while on testosterone therapy.
Contraindications[edit | edit source]
Testosterone propionate/testosterone ketolaurate is contraindicated in individuals with known hypersensitivity to the drug, in males with breast or prostate cancer, and in women who are pregnant or may become pregnant.
See Also[edit | edit source]
References[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD