Testosterone–cortisol ratio

Testosterone–cortisol ratio is a biomarker used in sports medicine and endocrinology to measure the balance between anabolic and catabolic metabolic processes in the body. This ratio is often used to assess the physiological stress response and recovery in athletes, as well as the potential for overtraining or under-recovery.

Overview

The testosterone to cortisol ratio is calculated by dividing the concentration of testosterone by the concentration of cortisol in the blood. Both hormones are produced by the adrenal glands and have opposing effects on the body. Testosterone is an anabolic hormone that promotes tissue growth and repair, while cortisol is a catabolic hormone that breaks down tissue to provide energy.

Physiological Significance

The testosterone-cortisol ratio can provide insight into an individual's physiological state. A high ratio indicates a predominance of anabolic processes, which can be associated with improved performance and recovery in athletes. Conversely, a low ratio indicates a predominance of catabolic processes, which can be associated with stress, overtraining, and potential for injury.

Clinical Applications

In sports medicine, monitoring the testosterone-cortisol ratio can help to prevent overtraining and under-recovery in athletes. It can also be used in endocrinology to assess the balance of anabolic and catabolic processes in patients with conditions such as Cushing's syndrome or Addison's disease.

Research

Research on the testosterone-cortisol ratio has focused on its potential as a biomarker for overtraining in athletes. Studies have found that a low ratio can predict overtraining and under-recovery, while a high ratio can predict improved performance and recovery.

See Also

• Hormone
• Endocrinology
• Sports Medicine
• Cushing's Syndrome
• Addison's Disease