Thyrotoxic myopathy

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Thyrotoxic myopathy
Synonyms
Pronounce N/A
Specialty Endocrinology, Neurology
Symptoms Muscle weakness, muscle wasting, fatigue
Complications N/A
Onset Gradual
Duration Variable
Types N/A
Causes Hyperthyroidism
Risks
Diagnosis Clinical diagnosis, Electromyography, Thyroid function tests
Differential diagnosis Polymyositis, Dermatomyositis, Myasthenia gravis
Prevention N/A
Treatment Antithyroid medication, Beta blockers, Radioactive iodine therapy, Thyroidectomy
Medication N/A
Prognosis Generally good with treatment
Frequency Common in individuals with hyperthyroidism
Deaths N/A


Thyrotoxic myopathy is a neuromuscular disorder that may accompany hyperthyroidism (Graves' disease, caused by overproduction of the thyroid hormone thyroxine).

Symptoms[edit | edit source]

Symptoms may include muscle weakness, myalgias (muscle tenderness), wasting of the pelvic girdle and shoulder muscles, fatigue, and/or heat intolerance.

Associated conditions[edit | edit source]

Thyroid myopathy may be associated with rhabdomyolysis (acute muscle breakdown), damage to the muscles that control eye movement, and temporary, but severe, attacks of muscle weakness that are associated with low blood potassium levels (known as periodic paralysis).

Prognosis[edit | edit source]

Prognosis is good with proper diagnosis and treatment.

Treatment[edit | edit source]

Treatment involves treated the underlying thyrotoxicosis and may include thyroid drugs, radioactive iodine, and sometimes partial or complete surgical removal of the thyroid.  

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