Transient acantholytic dermatosis

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Transient Acantholytic Dermatosis

File:Transient Acantholytic Dermatosis.jpg
A typical presentation of Transient Acantholytic Dermatosis

Transient Acantholytic Dermatosis (TAD), also known as Grover's Disease, is a skin condition characterized by the sudden onset of red, itchy bumps on the torso and upper arms. It was first described by Dr. Ralph W. Grover in 1970.

Etiology[edit | edit source]

The exact cause of TAD is unknown, but it is believed to be related to damage to the epidermis, the outermost layer of the skin. Factors that may contribute to the development of TAD include heat, sweating, and friction. It is also more common in men over the age of 40.

Symptoms[edit | edit source]

The primary symptom of TAD is the appearance of small, red, itchy bumps on the torso and upper arms. These bumps may also appear on the legs and face. In some cases, the bumps may blister or become filled with pus.

Diagnosis[edit | edit source]

Diagnosis of TAD is typically made based on the appearance of the skin and the patient's symptoms. A skin biopsy may be performed to confirm the diagnosis and rule out other skin conditions.

Treatment[edit | edit source]

Treatment for TAD is aimed at relieving symptoms and may include topical corticosteroids, antihistamines, and moisturizers. In severe cases, oral retinoids or phototherapy may be used.

Prognosis[edit | edit source]

TAD is a chronic condition, but it is not life-threatening. The symptoms may come and go, and in some cases, they may resolve on their own without treatment.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD