Tridihexethyl chloride
Tridihexethyl Chloride is a pharmacological agent primarily used as an antispasmodic. It is a type of quaternary ammonium compound and is classified under the category of muscarinic antagonists.
Pharmacology[edit | edit source]
Tridihexethyl Chloride works by blocking the muscarinic acetylcholine receptors, which are found in the autonomic nervous system. By doing so, it inhibits the action of acetylcholine, a neurotransmitter that plays a crucial role in transmitting signals in the nervous system. This results in the relaxation of smooth muscles, thus reducing spasms.
Medical Uses[edit | edit source]
Tridihexethyl Chloride is used in the treatment of various conditions that involve spasms of the smooth muscles. These include gastrointestinal disorders such as irritable bowel syndrome and peptic ulcer disease, as well as certain urinary disorders.
Side Effects[edit | edit source]
Like other muscarinic antagonists, Tridihexethyl Chloride can cause a range of side effects. These may include dry mouth, blurred vision, constipation, and difficulty in urination. In rare cases, it may also lead to glaucoma or cardiac arrhythmia.
Contraindications[edit | edit source]
Tridihexethyl Chloride is contraindicated in patients with myasthenia gravis, glaucoma, and severe ulcerative colitis. It should also be used with caution in elderly patients and those with cardiovascular disease.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD