Tumid lupus erythematosus

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Tumid lupus erythematosus
Synonyms TLE
Pronounce N/A
Specialty N/A
Symptoms Erythema, edema, plaques
Complications Scarring, skin atrophy
Onset Variable
Duration Chronic
Types N/A
Causes Unknown, possibly autoimmune disease
Risks Sun exposure, genetic predisposition
Diagnosis Skin biopsy, clinical examination
Differential diagnosis Discoid lupus erythematosus, polymorphous light eruption, sarcoidosis
Prevention N/A
Treatment Topical corticosteroids, antimalarials, sun protection
Medication N/A
Prognosis Generally good with treatment
Frequency Rare
Deaths N/A


Tumid lupus erythematosus is a rare and less severe subtype of lupus erythematosus, a chronic autoimmune disease. It is characterized by erythematous, edematous, non-scarring plaques on sun-exposed skin, without systemic involvement.

Signs and Symptoms[edit | edit source]

Patients with tumid lupus erythematosus typically present with single or multiple erythematous, edematous, and non-scarring plaques. These plaques are often located on sun-exposed areas of the skin, such as the face, V area of the neck, and the upper trunk. The plaques may be asymptomatic or associated with mild pruritus.

Causes[edit | edit source]

The exact cause of tumid lupus erythematosus is unknown. However, it is believed to be an autoimmune disorder, where the body's immune system attacks its own cells and tissues. Exposure to sunlight may trigger the condition in susceptible individuals.

Diagnosis[edit | edit source]

The diagnosis of tumid lupus erythematosus is based on clinical features, histopathological findings, and the absence of systemic involvement. A skin biopsy is often performed to confirm the diagnosis.

Treatment[edit | edit source]

Treatment of tumid lupus erythematosus primarily involves avoiding sun exposure and using sun-protective measures. Topical corticosteroids and antimalarial drugs, such as hydroxychloroquine, may also be used.

Prognosis[edit | edit source]

The prognosis for tumid lupus erythematosus is generally good, as it does not typically progress to systemic lupus erythematosus or cause scarring. However, regular follow-up is necessary to monitor for potential development of systemic disease.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD