Tumor-associated glycoprotein 72

From WikiMD's Wellness Encyclopedia

Tumor-associated glycoprotein 72 (TAG-72) is a glycoprotein found on the surface of many cancer cells, including ovary, [citation needed]

breast, colon, lung, and pancreatic cancers.

TAG-72 is a tumor marker measured with radioimmunoassays like CA 72-4, which uses the monoclonal antibodies indium (111In) satumomab pendetide and iodine (125I) minretumomab.

TAG-72 is also the target of the anti-cancer drugs anatumomab mafenatox and minretumomab.

References[edit | edit source]

 This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".


Contributors: Prab R. Tumpati, MD