Tyzeka

Tyzeka (also known as Telbivudine) is an antiviral drug used in the treatment of Hepatitis B infection. It is a synthetic thymidine nucleoside analogue, and it works by inhibiting the replication of viral DNA.

Mechanism of Action

Tyzeka is a direct inhibitor of Hepatitis B virus (HBV) replication. It is incorporated into the viral DNA by the HBV polymerase, leading to DNA chain termination. This process inhibits the replication of the virus and reduces the amount of virus in the body.

Uses

Tyzeka is used for the treatment of chronic Hepatitis B in adults with evidence of viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.

Side Effects

Common side effects of Tyzeka include fatigue, headache, dizziness, nausea, and diarrhea. Serious side effects may include peripheral neuropathy and myopathy.

Drug Interactions

Tyzeka may interact with other drugs, including those that are also metabolized by the kidneys. It is important to inform healthcare providers of all medications being taken, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Precautions

Before starting treatment with Tyzeka, patients should inform their healthcare provider if they have kidney disease, a history of muscle problems, or if they are pregnant or planning to become pregnant.

See Also

• Hepatitis B
• Antiviral drug
• Polymerase