U-47700
Synthetic opioid analgesic
U-47700 is a synthetic opioid analgesic drug developed by Upjohn in the 1970s. It is structurally related to other opioids such as AH-7921 and is known for its potent analgesic effects. U-47700 has gained notoriety as a designer drug and has been associated with numerous cases of overdose and fatalities.
Chemical structure and properties[edit | edit source]
U-47700 is a member of the benzamide class of opioids. Its chemical structure is characterized by a 3,4-dichlorophenyl group attached to a methanone moiety, with a dimethylamino group at the 1-position and a methyl group at the 2-position of the propyl chain. This structure contributes to its high affinity for the mu-opioid receptor, which is responsible for its analgesic and euphoric effects.
Pharmacology[edit | edit source]
U-47700 acts primarily as a mu-opioid receptor agonist, similar to other opioids such as morphine and fentanyl. It produces effects such as pain relief, sedation, and euphoria. However, it also carries a high risk of respiratory depression, which can be fatal in overdose situations. The potency of U-47700 is estimated to be several times that of morphine.
Legal status[edit | edit source]
Due to its potential for abuse and associated health risks, U-47700 has been classified as a controlled substance in many countries. In the United States, it was temporarily placed in Schedule I of the Controlled Substances Act in 2016, indicating that it has a high potential for abuse and no accepted medical use.
Health risks and safety[edit | edit source]
The use of U-47700 has been linked to numerous adverse effects, including respiratory depression, cardiac arrest, and death. It is often found in combination with other substances, which can increase the risk of overdose. Users may also experience withdrawal symptoms similar to those of other opioids.
Related pages[edit | edit source]
References[edit | edit source]
Chemical structure of U-47700
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