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Uveitis–Glaucoma–Hyphema Syndrome (UGHS) is a rare and complex ocular condition that involves inflammation of the uvea (Uveitis), increased intraocular pressure (Glaucoma), and bleeding in the anterior chamber of the eye (Hyphema).

Etiology

UGHS is typically associated with trauma or surgery, particularly intraocular surgeries such as cataract extraction. It can also occur spontaneously in rare cases. The exact cause of UGHS is not well understood, but it is thought to involve a combination of inflammatory, vascular, and mechanical factors.

Clinical Presentation

Patients with UGHS typically present with symptoms of ocular pain, redness, and decreased vision. On examination, there may be evidence of inflammation in the anterior chamber (Anterior Uveitis), elevated intraocular pressure, and blood in the anterior chamber.

Diagnosis

The diagnosis of UGHS is primarily clinical, based on the characteristic triad of uveitis, glaucoma, and hyphema. Additional tests such as ocular ultrasound, fluorescein angiography, and optical coherence tomography may be used to confirm the diagnosis and assess the extent of the disease.

Treatment

The treatment of UGHS is aimed at controlling the inflammation, reducing the intraocular pressure, and managing the hyphema. This may involve the use of topical and systemic medications, as well as surgical interventions in severe cases.

Prognosis

The prognosis of UGHS is variable, depending on the severity of the disease and the response to treatment. In some cases, the disease can lead to permanent vision loss.

See Also

• Uveitis
• Glaucoma
• Hyphema
• Anterior Uveitis

References

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