Iodixanol

From WikiMD's Wellness Encyclopedia

(Redirected from Visipaque 320)

Iodixanol is a non-ionic, iso-osmolar radiocontrast agent used primarily in diagnostic imaging. It is commonly utilized in various radiographic studies such as Computed Tomography (CT) scans, X-rays, and angiography. Iodixanol helps in enhancing the visibility of vascular structures and organs, facilitating the diagnosis of diseases and abnormalities.

Composition and Properties[edit | edit source]

Iodixanol is a dimeric iodinated contrast medium, meaning it contains two iodine molecules, which are responsible for its radiopaque properties. Its chemical formula is C35H44I6N6O15, and it has a molecular weight of approximately 1550 g/mol. Being iso-osmolar, iodixanol has the same osmolality as blood, which reduces the risk of osmotic-induced side effects that can occur with other contrast agents.

Indications[edit | edit source]

Iodixanol is indicated for a wide range of diagnostic tests, including but not limited to:

Mechanism of Action[edit | edit source]

As a contrast agent, iodixanol works by increasing the contrast of bodily structures and fluids within the imaging field. The iodine atoms within the molecule absorb X-rays more effectively than the surrounding tissues. This differential absorption enhances the visibility of structures such as blood vessels, making them appear distinct from other tissues on the radiographic image.

Administration[edit | edit source]

Iodixanol is administered intravenously or intra-arterially, depending on the type of diagnostic test being performed. The dosage varies based on the specific examination, the area of interest, and the patient's body weight and renal function. It is essential to properly hydrate patients before and after the administration of iodixanol to promote excretion and minimize renal stress.

Side Effects[edit | edit source]

While iodixanol is generally well-tolerated due to its iso-osmolar nature, some patients may experience side effects, including:

Precautions[edit | edit source]

Before administering iodixanol, it is crucial to assess the patient's history for any previous reactions to contrast media, current medications, and existing conditions such as renal impairment or thyroid disorders. It is also important to monitor patients for adverse reactions during and after the procedure.

Conclusion[edit | edit source]

Iodixanol is a valuable tool in diagnostic imaging, offering high-quality images with a reduced risk of osmotic-induced side effects. Its use across a broad spectrum of radiographic studies underscores its versatility and effectiveness as a contrast agent. However, careful patient assessment and monitoring are essential to minimize the risk of adverse effects and ensure patient safety.


WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD