ZNF346
ZNF346 (Zinc Finger Protein 346) is a protein that in humans is encoded by the ZNF346 gene. This protein is a member of the zinc finger family of proteins, which are regulatory proteins that can bind to DNA, RNA, protein and/or lipid substrates.
Function[edit | edit source]
ZNF346 is a transcription factor that can bind to DNA and regulate the expression of other genes. It is involved in various biological processes, including cell differentiation, cell growth, apoptosis, and immune response.
Structure[edit | edit source]
The ZNF346 protein contains several zinc finger domains, which are regions of the protein that can bind to specific sequences of DNA. These domains are characterized by the presence of zinc ions, which are coordinated by cysteine and histidine residues.
Clinical significance[edit | edit source]
Mutations in the ZNF346 gene have been associated with various diseases, including cancer, autoimmune diseases, and neurodegenerative diseases. Further research is needed to fully understand the role of ZNF346 in these diseases.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD